Research
Huntington's disease
Validating the use of digital health technologies to monitor disease symptoms in Huntington disease, including physical activity level, falls, chorea, and speech difficulties.
Huntington's disease (HD) is a progressive, inherited neurodegenerative disorder that is characterized by a combination of motor, cognitive, and psychiatric symptoms. HD motor symptoms include involuntary jerking or writhing movements (chorea), muscle problems such as rigidity or muscle contracture (dystonia), slow or abnormal eye movements, impaired gait, posture, and balance, and difficulty with speech or swallowing.
Our research in HD, supported by $2.5M of funding from the NIH, is focused on developing and validating a multi-modal digital health technology for monitoring motor symptoms of prodromal HD and HD. This includes the use of 1) wearable sensors for monitoring physical activity, falls, upper limb function and chorea, and 2) BioDigit Speech to assess speech difficulties and dysarthria.
Our clinical studies in HD
BioDigit HD
Clinicaltrials.gov ID: NCT03599076
Status: Completed
Number of participants: 44
Monitoring period: Up to 2.5 years
Study product: PAMSys, PAMSys Fall, PAMSys ULM, BioDigit Speech
Our research partners
